Monday, December 3, 2012

What type of vitamin and mineral deficiencies lead to depression?***?

Q. I've had mild depression for a long long long time...(maybe 10 years). I'm just wondering if perhaps certain deficiencies lead to depression and if there is a way I can be tested for deficiencies. For example, I know a lack of vitamin B can have effect on mood. How do they test vitamin b levels?
And what about hormonal imbalances? Can that lead to depression as well?

A. Deficiencies in the following vitamins and minerals can lead to chemical imbalances in the brain that can cause symptoms of depression -

- B Vitamins (e.g. B1, B6, B12, B9)
- Vitamin D
- Selenium

Clinical research shows that a diet and lifestyle contributing to low levels of these vitamins and minerals may contribute to feelings of depression, anxiety and fatigue. Unfortunately, many adults do not receive the optimal amount of these vital nutrients.

Hormonal imbalances can also lead to signs and symptoms of depression as well. According to allaboutdepression.com, "The hypothalamus also controls the function of the pituitary gland which in turn regulates key hormones. Other structures within the limbic system that are associated with emotional reaction are the amygdala and hippocampus. The activities of the limbic are so important and complex that disturbances in any part of it, including how neurotransmitters function, could affect your mood and behavior."


what type of vitamin and mineral deficiencies lead to depression?
Q. I've had mild depression for a long long long time...(maybe 10 years). I'm just wondering if perhaps certain deficiencies lead to depression and if there is a way I can be tested for deficiencies. For example, I know a lack of vitamin B can have effect on mood. How do they test vitamin b levels?
And what about hormonal imbalances? Can that lead to depression as well?

A. Deficiencies in the following vitamins and minerals can lead to chemical imbalances in the brain that can cause symptoms of depression -

- B Vitamins (e.g. B1, B6, B12, B9)
- Vitamin D
- Selenium

Clinical research shows that a diet and lifestyle contributing to low levels of these vitamins and minerals may contribute to feelings of depression, anxiety and fatigue. Unfortunately, many adults do not receive the optimal amount of these vital nutrients.

Hormonal imbalances can also lead to signs and symptoms of depression as well. According to allaboutdepression.com, "The hypothalamus also controls the function of the pituitary gland which in turn regulates key hormones. Other structures within the limbic system that are associated with emotional reaction are the amygdala and hippocampus. The activities of the limbic are so important and complex that disturbances in any part of it, including how neurotransmitters function, could affect your mood and behavior."


Is anyone besides me aware that soy fed to chickens spikes their MSG content?
Q. I can't eat the stuff and had to find out the hard way -- muscle cramps and vitamin B deficiency symptoms when I was heavier... headaches and heart palpitations when my cholesterol was more in line.

A. no I didnt but thanx I am allergic to msg and have the same symptoms they have recently found out that soy really isnt that good for you


How long does it take Vitamin B-12 to be absorbed into my system?
Q. After research as to my lack of energy lately, I came across a few people who suggested taking Vitamin B-12 as it is responsible for energy metabolisim and I may be deficient. After reading some blogs and the packaging on the actual vitamins I decided to go with the sublingul (under the tongue) form as it is abosrbed into my system faster. I am taking the reccommended dosage once a day and It is working beautifuly although I'm wondering if I am feeling energy when I do because the Vitamin kicks in or if it's a placibo effect. Does anybody know how long it takes to be absorbed...minutes...hours...your response is much appreciated.

A. Physiology of Absorption, Metabolism, and Excretion

Following ingestion, absorption of thiamin occurs mainly in the jejunum, at lower concentrations as an active, carrier-mediated system involving phosphorylation and at higher concentrations by passive diffusion. Thiamin is transported in blood both in erythrocytes and plasma.

Only a small percentage of a high dose of thiamin is absorbed, and elevated serum values result in active urinary excretion of the vitamin (Davis et al., 1984). After an oral dose of thiamin, peak excretion occurs in about 2 hours, and excretion is nearly complete after 4 hours (Levy and Hewitt, 1971; Morrison and Campbell, 1960). In a study by Davis and colleagues (1984), a 10-mg oral dose of thiamin was given in water, and the mean serum thiamin peaked at 24 nmol/L (7.2 µg/L) �42 percent above baseline. Within 6 hours the serum thiamin concentration had returned to baseline, 17 nmol/L (5.2 µg/L). Prompt urinary excretion of thiamin was also reported by Najjar and Holt (1940) and McAlpine and Hills (1941).

With higher pharmacological levels, namely repetitive 250-mg amounts taken orally and 500 mg given intramuscularly, nearly 1 week was required for steady state plasma concentrations to be reached; a mean elimination half-life of 1.8 days was estimated (Royer-Morrot et al., 1992).

Total thiamin content of the adult human has been estimated to be approximately 30 mg, and the biological half-life of the vitamin is probably in the range of 9 to 18 days (Ariaey-Nejad et al., 1970).
Clinical Effects of Inadequate Intake

Early stages of thiamin deficiency may be accompanied by non-specific symptoms that may be overlooked or easily misinterpreted (Lonsdale and Shamberger, 1980). The clinical signs of deficiency include anorexia; weight loss; mental changes such as apathy, decrease in short-term memory, confusion, and irritability; muscle weakness; and cardiovascular effects such as an enlarged heart (Horwitt et al., 1948; Inouye and Katsura, 1965; Platt, 1967; Williams et al., 1942; Wilson, 1983). In wet beriberi, edema occurs; in dry





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