What Is Scurvy? What Causes Scurvy?

Scurvy

Megaloblastic anemia, vitamin B12 or folate deficiency

Megaloblastic anemia (or megaloblastic anaemia) is an anemia (of macrocytic classification) that results from inhibition of DNA synthesis in red blood cell production.[1] When DNA synthesis is impaired, the cell cycle cannot progress from the G2 growth stage to the mitosis (M) stage. This leads to continuing cell growth without division, which presents as macrocytosis.
The defect in red cell DNA synthesis is most often due to hypovitaminosis, specifically a deficiency of vitamin B12 and/or folic acid. Vitamin B12 deficiency alone will not cause the syndrome in the presence of sufficient folate, for the mechanism is loss of B12 dependent folate recycling, followed by folate-deficiency loss of nucleic acid synthesis (specifically thymine), leading to defects in DNA synthesis. Folic acid supplementation in the absence of vitamin B12 prevents this type of anemia (although other vitamin B12-specific pathologies continue).
Megaloblastic anemia not due to hypovitaminosis may be caused by antimetabolites that poison DNA production directly, such as some chemotherapeutic or antimicrobial agents (for example azathioprine or trimethoprim).
The pathological state of megaloblastosis is characterized by many large immature and dysfunctional red blood cells (megaloblasts) in the bone marrow[2] and also by hypersegmented neutrophils (those exhibiting five or more nuclear lobes ("segments"), with up to four lobes being normal). These hypersegmented neutrophils are found in the "peripheral blood" (i.e., a diagnostic smear of a blood-sample taken from the circulation).

Megaloblastic Anemia Causes

• Vitamin B12 deficiency

Pellagra, the four D's ended by Death

Pellagra

Vitamin D Deficiency Symptoms

Vitamin D is the vitamin that the skin produces when it is exposed to ultraviolet rays from the sun. Vitamin D actually functions as a steroid hormone that can influence gene expression in human cells. I have written quite a few posts about Vitamin D before, here I will go in to more detail on Vitamin D Deficiency Symptoms.

I would like to divide Vitamin D deficiency symptoms into two categories: short-term symptoms and long-term symptoms. Short term symptoms would be something that you might experience right now, while long term symptoms would be something you might not experience until in old age.

Short term Vitamin D deficiency symptoms

Rickets:

Beriberi or Thiamine Deficiency

Definition of Beriberi:

Beriberi is a disease in which the body does not have enough

Xerophthalmia, When You've Got No Tears

Xerophthalmia

Mengatasi Hidung Tersumbat Pada Bayi

Saat hidung bayi Anda tersumbat, ia akan tersiksa. Mau bobok tidak enak, menyusu pun kehabisan nafas. Hidung tersumbat merupakan gejala awal influensa.

Hidung bayi beringus, namun karena udara kering, ingus mengering sehingga menutup dan menyumbat hidung. Penting untuk mengeluarkan ingus dari hidung bayi agar pernafasannya lega kembali.

Bila hidung tersumbat disertai dengan demam, batuk tak kunjung berhenti, atau jika ingus berwarna kuning atau hijau, bawalah bayi ke dokter. Berikut Cara